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1

Monoclonal antibodies to herpes simplex virus type 1 glycoproteins show that epitope location influences virus neutralization

N. B. La Thangue, W. L. Chan, June D. Almeida

Journal:

Journal of Medical Virology

Year:

1984

Language:

english

File:

PDF, 1.17 MB

english, 1984

2

The predominant E2F complex in human primary haemopoietic cells and in AML blasts contains E2F-4, DP-1 and p130

C. D. WILLIAMS, D. C. LINCH, T. S. SØRENSEN, N. B. LA THANGUE, N. S. B. THOMAS

Journal:

British Journal of Haematology

Year:

1997

Language:

english

File:

PDF, 643 KB

english, 1997

3

The characterization and purification of DNA binding proteins present within herpes simplex virus infected cells using monoclonal antibodies

N. B. la Thangue, W. L. Chan

Journal:

Archives of Virology

Year:

1984

Language:

english

File:

PDF, 1.50 MB

english, 1984

4

Control of the p53 response

Nicholas B. La Thangue

Journal:

Year:

2007

Language:

english

File:

PDF, 48 KB

english, 2007

5

10.1038/35008660

La Thangue, Nicholas B., Morris, Lorna, Allen, K. Elizabeth

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 333 KB

english, 2000

6

10.1038/35083062

Chan, Ho Man, Krstic-Demonacos, Marija, Smith, Linda, Demonacos, Constantinos, Thangue, Nicholas B. La

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 492 KB

english, 2001

7

Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

Bandara, Lasantha R., La Thangue, Nicholas B.

Journal:

Year:

1991

File:

PDF, 444 KB

1991

8

Cyclin A and the retinoblastoma gene product complex with a common transcription factor

Bandara, Lasantha R., Adamczewski, Jörg P., Hunt, Tim, La Thangue, Nicholas B.

Journal:

Year:

1991

File:

PDF, 473 KB

1991

9

A new component of the transcription factor DRTF1/E2F

Girling, Rowena, Partridge, Janet F., Bandara, Lasantha R., Burden, Neil, Totty, Nicholas F., Hsuan, J. Justin, Thangue, Nicholas B. La

Journal:

Year:

1993

File:

PDF, 688 KB

1993

10

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

Martin, Klaus, Trouche, Didier, Hagemeier, Christian, Sorensen, Troels S., La Thangue, Nicholas B., Kouzarides, Tony

Journal:

Year:

1995

File:

PDF, 424 KB

1995

11

E2F-1 regulation by an unusual DNA damage-responsive DP partner subunit

Ingram, L, Munro, S, Coutts, A S, La Thangue, N B

Journal:

Cell Death & Differentiation

Year:

2010

Language:

english

File:

PDF, 894 KB

english, 2010

12

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein

Carr, Simon M, Munro, Shonagh, Kessler, Benedikt, Oppermann, Udo, La Thangue, Nicholas B

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 1.49 MB

english, 2010

13

ATM and Chk2 kinase target the p53 cofactor Strap

Adams, Cassandra J, Graham, Anne L, Jansson, Martin, Coutts, Amanda S, Edelmann, Mariola, Smith, Linda, Kessler, Benedikt, La Thangue, Nicholas B

Journal:

Year:

2008

Language:

english

File:

PDF, 592 KB

english, 2008

14

A transcription cofactor required for the heat-shock response

Xu, Danmei, Zalmas, L Panagiotis, La Thangue, Nicholas B

Journal:

Year:

2008

Language:

english

File:

PDF, 278 KB

english, 2008

15

Apoptosis induced in mammalian cells by small peptides that functionally antagonize the Rb-regulated E2F transcription factor

Bandara, Lasantha R., Girling, Rowena, Thangue, Nicholas B. La

Journal:

Nature Biotechnology

Year:

1997

File:

PDF, 874 KB

1997

16

A mismatched role for Bcl-2

La Thangue, Nicholas B.

Journal:

Nature Cell Biology

Year:

2005

Language:

english

File:

PDF, 126 KB

english, 2005

17

The yin and yang of E2F-1: balancing life and death

La Thangue, Nicholas B.

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 105 KB

english, 2003

18

A new effector pathway links ATM kinase with the DNA damage response

Demonacos, Constantinos, Krstic-Demonacos, Marija, Smith, Linda, Xu, Danmei, O'Connor, Darran P., Jansson, Martin, Thangue, Nicholas B. La

Journal:

Nature Cell Biology

Year:

2004

Language:

english

File:

PDF, 1.42 MB

english, 2004

19

Arginine methylation regulates the p53 response

Jansson, Martin, Durant, Stephen T., Cho, Er-Chieh, Sheahan, Sharon, Edelmann, Mariola, Kessler, Benedikt, La Thangue, Nicholas B.

Journal:

Nature Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.83 MB

english, 2008

20

Chk2 activates E2F-1 in response to DNA damage

Stevens, Craig, Smith, Linda, La Thangue, Nicholas B.

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 2.00 MB

english, 2003

21

Lysine methylation regulates the pRb tumour suppressor protein

Inche, A, Carr, S, La Thangue, N B, Munro, S, Khaire, N

Journal:

Year:

2010

Language:

english

File:

PDF, 766 KB

english, 2010

22

Hypoxia-driven cell motility reflects the interplay between JMY and HIF-1α

Coutts, A S, Pires, I M, Weston, L, Buffa, F M, Milani, M, Li, J-L, Harris, A L, Hammond, E M, La Thangue, N B

Journal:

Year:

2011

Language:

english

File:

PDF, 901 KB

english, 2011

23

14-3-3 proteins integrate E2F activity with the DNA damage response

Milton, Alasdair H, Khaire, Nandkumar, Ingram, Laura, O'donnell, Amanda J, La Thangue, Nicholas B

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 357 KB

english, 2006

24

DNA-damage-responsive acetylation of pRb regulates binding to E2F-1

Markham, Douglas, Munro, Shonagh, Soloway, Judith, O'Connor, Darran P, La Thangue, Nicholas B

Journal:

Year:

2006

Language:

english

File:

PDF, 209 KB

english, 2006

25

Mdm2 targets the p53 transcription cofactor JMY for degradation

Coutts, Amanda S, Boulahbel, Houda, Graham, Anne, La Thangue, Nicholas B

Journal:

Year:

2006

Language:

english

File:

PDF, 206 KB

english, 2006

26

DNA-damage response control of E2F7 and E2F8

Panagiotis Zalmas, L, Zhao, Xiujie, Graham, Anne L, Fisher, Rebecca, Reilly, Carmel, Coutts, Amanda S, La Thangue, Nicholas B

Journal:

Year:

2008

Language:

english

File:

PDF, 333 KB

english, 2008

27

Functional interplay between p53 and E2F through co-activator p300

Lee, Chang-Woo, Sørensen, Troels S, Shikama, Noriko, Thangue, Nicholas B La

Journal:

Year:

1998

Language:

english

File:

PDF, 571 KB

english, 1998

28

Promoter specificity and stability control of the p53-related protein p73

Lee, Chang-Woo, La Thangue, Nicholas B

Journal:

Year:

1999

Language:

english

File:

PDF, 451 KB

english, 1999

29

Control of E2F activity by p21Waf1/Cip1

Delavaine, Laurent, La Thangue, Nicholas B

Journal:

Year:

1999

Language:

english

File:

PDF, 503 KB

english, 1999

30

Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein

Chan, Ho Man, Smith, Linda, La Thangue, Nicholas B

Journal:

Year:

2001

Language:

english

File:

PDF, 503 KB

english, 2001

31

p14ARF regulates E2F activity

Mason, Sarah L, Loughran, &#214, onagh, La Thangue, Nicholas B

Journal:

Year:

2002

Language:

english

File:

PDF, 383 KB

english, 2002

32

E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains

Logan, Nicola, Delavaine, Laurent, Graham, Anne, Reilly, Carmel, Wilson, Jon, Brummelkamp, Thijn R, Hijmans, E Marielle, Bernards, René, La Thangue, Nicholas B

Journal:

Year:

2004

Language:

english

File:

PDF, 620 KB

english, 2004

33

E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7

Logan, Nicola, Graham, Anne, Zhao, Xuijie, Fisher, Rebecca, Maiti, Baidehi, Leone, Gustavo, Thangue, Nicholas B La

Journal:

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

34

A functionally distinct member of the DP family of E2F subunits

Milton, A, Luoto, K, Ingram, L, Munro, S, Logan, N, Graham, A L, Brummelkamp, T R, Hijmans, E M, Bernards, R, La Thangue, N B

Journal:

Year:

2006

Language:

english

File:

PDF, 210 KB

english, 2006

35

Predictive biomarkers: a paradigm shift towards personalized cancer medicine

La Thangue, Nicholas B., Kerr, David J.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2011

Language:

english

File:

PDF, 653 KB

english, 2011

36

Introduction: Cell cycle regulation and cancer

Nicholas B. La Thangue

Journal:

Seminars in Cancer Biology

Year:

1995

Language:

english

File:

PDF, 17 KB

english, 1995

37

Transcriptional induction of cellular gene expression during lytic infection with herpes simplex virus

L. M. Kemp, P. M. Brickell, N. B. La Thangue, D. S. Latchman

Journal:

Bioscience Reports

Year:

1986

Language:

english

File:

PDF, 563 KB

english, 1986

38

Transcriptional complexity

N.B. La Thangue, L.H. Johnston

Journal:

Current Biology

Year:

1993

Language:

english

File:

PDF, 667 KB

english, 1993

39

A structural similarity between mammalian and yeast transcription factors for cell-cycle-regulated genes

Nicholas B. La Thangue, William R. Taylor

Journal:

Trends in Cell Biology

Year:

1993

Language:

english

File:

PDF, 611 KB

english, 1993

40

Histone deacetylase inhibitors open new doors in cancer therapy

Fiona McLaughlin, Nicholas B La Thangue

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

41

Genome-wide Loss-of-Function Screen Reveals an Important Role for the Proteasome in HDAC Inhibitor-Induced Apoptosis

Susan Fotheringham, Mirjam T. Epping, Lindsay Stimson, Omar Khan, Victoria Wood, Francesco Pezzella, René Bernards, Nicholas B. La Thangue

Journal:

Year:

2009

Language:

english

File:

PDF, 1.46 MB

english, 2009

42

E2F proteins

Öonagh Loughran, Nicholas B La Thangue

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 196 KB

english, 2002

43

Stimulating an appetite: Gene Regulation: A Eukaryotic Perspective (2nd edn) by David Latchman, Chapman & Hall, 1994. £19.99 (271 pages) ISBN 0 412 60200 8

Nicolas B. La Thangue

Journal:

Trends in Cell Biology

Year:

1995

Language:

english

File:

PDF, 312 KB

english, 1995

44

Chromatin research gathers pace

Jonathan Lyon, Nicholas B. La Thangue

Journal:

Trends in Cell Biology

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

45

The cell cycle, chromatin and cancer: mechanism-based therapeutics come of age

Fiona McLaughlin, Paul Finn, Nicholas B La Thangue

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

46

Keynote review: Chromatin control and cancer-drug discovery: realizing the promise

Adam G. Inche, Nicholas B. La Thangue

Journal:

Drug Discovery Today

Year:

2006

Language:

english

File:

PDF, 1.90 MB

english, 2006

47

The cell cycle and drug discovery: the promise and the hope

Gavin Brooks, Nicholas B La Thangue

Journal:

Drug Discovery Today

Year:

1999

Language:

english

File:

PDF, 205 KB

english, 1999

48

T-ARG-eting E2F-1 growth control

Moehlenbrink, Jutta, La Thangue, Nicholas B.

Journal:

Year:

2012

Language:

english

File:

PDF, 484 KB

english, 2012

49

A cellular protein related to heat-shock protein 90 accumulates during herpes simplex virus infection and is overexpressed in transformed cells

Nicholas B.La Thangue, David S. Latchman

Journal:

Experimental Cell Research

Year:

1988

Language:

english

File:

PDF, 2.63 MB

english, 1988

50

The p53 response: Emerging levels of co-factor complexity

Amanda S. Coutts, Nicholas B. La Thangue

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 282 KB

english, 2005